Morgagnian Cataract is recognized by the following codes as per the International Classification of Diseases (ICD) nomenclature:
ICD - 10
- H25.20 Age-related cataract, morgagnian type, unspecified eye
- H25.21 Age-related cataract, morgagnian type, right eye
- H25.22 Age-related cataract, morgagnian type, left eye
- H25.23 Age-related cataract, morgagnian type, bilateral
Morgagnian cataract is a form of hypermature cataract formed by liquefaction of the cortex and sinking of the dense nucleus to the bottom of the capsular bag. The name "Morgagnian" derives from Giovanni Battista Morgagni, the 18th century anatomical pathologist.
In most developed countries cataract surgeries are done as soon as it becomes visually disabling. But due to late presentation of the patients Morgagnian cataracts are commonly seen in developing countries.
It is commonly age related acquired condition. However, factors that increase the risk of cortical cataracts, like chronic sunlight exposure and uncontrolled diabetes, are the risk factors.
It appears that the Morgagnian cataract is a special form of cortico-nuclear cataract. It is assumed that the process of fibre dissolution which is encountered in cortical cataract in general is sped up and occurs en masse in the Morgagnian cataract. Histopathologically, accumulation of eosinophilic fluid between lens cells with displacement and degeneration of bordering cells characterize cortical cataracts. Spherical droplets or globules of released protein from the breakdown of cortical cell walls are called Morgagnian globules. These globules may accumulate and may eventually replace the entire cortex and result in a mature Morgagnian cataract. The central dense nucleus at this point would become gravity dependent often displaced inferiorly to the lower equatorial region of the lens within the capsular bag. 
Morgagnian cataract is a clinical diagnosis.
- Decreased visual acuity - gradually progressive and painless
- Dense nucleus floating freely in the liquified cortex
- Triangle sign - Slit lamp examination with a narrow-slit beam angled at 60° with a magnification of 16x-20x focused above the nucleus shows a triangular area bounded anteriorly and posteriorly by the anterior and posterior lens capsule and the base of the triangle formed by the lens nucleus. This finding is named because of the triangular space formed by the anterior and posterior lens capsule and the nucleus below. 
- Flecks of calcium deposits in the anterior capsule may be seen.
- Absence of red fundus glow in retinoscopy
- Blurring of vision and glare may be early signs of developing cataract
- Morgagnian cataracts will typically present with profound visual loss (hand-motions or light-perception)
- Morgagnian cataract may undergo spontaneous rupture into anterior chamber causing inflammatory reaction, which is known as phacoanaphylactic uveitis.
- Spontaneous rupture of lens capsule may cause secondary glaucoma.
- It may also be complicated with phacolytic glaucoma when the lens protein leaked through the anterior capsule clog the trabecular meshwork obstructing the aqueous outflow.
- Assessment of visual potential by checking accurate light projections and swinging flashlight test to detect a relative afferent pupillary defect.
- B-scan ultrasound study for posterior segment evaluation to rule out complicated co-existing intraocular diseases.
- Measurements of the corneal refractive power and immersion A-scan to determine the power of the IOL required.
- Inferiorly subluxated cataractous lens - The triangle sign can be helpful in making the correct diagnosis. A clear transparent space is observed above the cataractous lens in both the scenarios and can lead to confusion when examined under diffuse illumination with a slit lamp. The triangle sign is present in the cases of Morgagnian cataract with resorbed cortex due to the presence of the intact zonules and the capsular bag whereas it is absent in the cases of the inferiorly subluxated cataractous lens due to loss of zonules.
- White cataract
- Traumatic cataract
Surgical removal of the cataractous lens followed by intraocular lens implantation is the treatment modality of choice.
- Extracapsular Cataract extraction (ECCE), Small incision cataract surgery (SICS) or phacoemulsification can be performed for the cataract extraction. This is followed by intraocular lens implantation (posterior chamber intraocular lens (PCIOL )/ anterior chamber intraocular lens (ACIOL))
- Intraocular lens scaffold technique has been described to prevent posterior capsule rupture for phacoemulsification of a Morgagnian cataract. This technique uses the IOL as a scaffold to prevent the vulnerable posterior capsule from rupturing during nuclear emulsification in Morgagnian cataract. The technique prevents rupture of the floppy posterior capsule by providing a constant support to it. The scaffold provides stable inflation of the capsular bag and prevents inadvertent emulsification. Concurrently, it prevents dehiscence of weak zonular fibers by minimizing the stress on the zonular apparatus.
- Creation of continuous curvilinear capsulorhexis is challenging due to an often fibrous anterior capsule and increased intralenticular pressure. Increased intralenticular pressure may result in an Argentinian flag sign and radialized capsular tear with vitreous loss.
- The surgical view may be poor due to lack of red reflex or due to the leaked liquified cortical material into the anterior chamber.
- The posterior capsule is often floppy during nuclear removal, which often requires high energy to remove due to density. This can predispose to posterior capsule rent or rupture.
- Rarely, a Morgagnian cataract may be associated with an isolated posterior capsular opening without any history of trauma.
- Uncontrolled radial tear of anterior capsule
- Posterior capsular rent
- Nuclear drop into the vitreous
- Endothelial cell damage from excessive phacoemulsification energy
- Patients should be counseled about the increased risk of complications and the possible need of more than one surgeries to achieve the best visual outcome.
- Preoperative assessment for projection of light and relative afferent pupillary defect are important prognostic factors.
- Patients should also be explained about the possible binocular diplopia due to a longstanding loss of fusion.
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