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EyeWiki is where ophthalmologists, other physicians, patients and the public can view articles written by ophthalmologists, covering the vast spectrum of eye disease, diagnosis and treatment. Any qualified ophthalmologist or ophthalmologist in training is invited to contribute content to the wiki.

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Featured Article for March 14, 2020

Amniotic Membrane Transplant

Amniotic membrane, or amnion, is the innermost layer of the placenta and consists of a thick basement membrane and an avascular stromal matrix. Amniotic membrane transplantation has been used as a graft or as a dressing in different surgical subspecialties. In the field of ophthalmology, it is used broadly 1) to reconstruct the ocular surface after various procedures; 2) as a graft for ocular surface melts; and 3) as a bandage to promote healing in cases of persistent epithelial defects or ocular surface inflammation. All of these indications make use of amniotic membrane's ability to promote healing.

Live fetal membrane, which included both amnion and chorion, was first documented by De Rotth in 1940 for use in conjunctival reconstruction. A very low success rate was reported. During the same year, Brown used rabbit peritoneum as a temporary patch for ocular surface burns which Sorsby later modified with human amniotic membrane in 1946 and 1947. In 1995 Kim and Tseng reintroduced the idea of amniotic membrane for ophthalmic use which has since become increasingly popular.

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Editor-in-Chief 
Marcus Marcet, M.D.
Deputy Editor-in-Chief 
Cat Nguyen Burkat, MD FACS

Section Lead Editors

Cataract/Anterior Segment  
Alpa S. Patel, M.D.
Cornea/External Disease  
Vatinee Bunya, MD
Glaucoma  
Ahmad A. Aref, MD, MBA
Neuro-ophthalmology/Orbit  
Andrew Go Lee, MD
Ocular Trauma  
Anna Murchison, MD, MPH
Oculoplastics/Orbit  
Michael T Yen, MD
Oncology/Pathology  
Matthew W. Wilson, MD, FACS
Pediatric Ophthalmology/Strabismus  
Monte A Del Monte, MD
Refractive Management/Intervention  
Alaa Eldanasoury, MD
Retina/Vitreous  
Jennifer I Lim MD
Uveitis  
Alan Palestine, MD