Featured Article for June 30, 2018
Idiopathic Retinitis, Vasculitis, Aneurysms, and Neuroretinitis (IRVAN)
Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is a rare clinical entity of unknown etiology. Some authors have speculated an association with positive P-ANCA s (Perinuclear AntiNeutrophil Cytoplasmic Antibodies) systemic vasculitis and antiphospholipid syndrome. Idiopathic retinal vasculitis, aneurysms, and neuroretinitis or IRVAN syndrome was first described in 1995 although case reports have been published since the 1970s.