Featured Article for August 14, 2021
Neuro Ophthalmic Complications of Immune Checkpoint Inhibitors
The use of immune checkpoint inhibitors (ICI) in treatment of malignancy has increased in prominence due to increasing research showing clinical benefit in multiple different malignancy types. This form of treatment, which involves activating the individual’s own immune system to target malignant cells, can sometimes cause unique adverse effects, which primarily relate to the activation or reactivation of autoimmune diseases. It is important to note however, that neuro ophthalmic manifestations may also be a direct result of the disease, or other treatments of the disease, and this should be taken into consideration as well.