File:ChlorpromazineVery-close-up.jpg

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Summary

Contributor: Elizabeth Gauger, MD Photographer: D. Brice Critser, CRA, OCT-C Corneal and lenticular pigmentation from long-term chlorpromazine use

59-year-old male with history of schizophrenia and long-term chlorpromazine (thorazine) treatment. His ocular exam is notable for fine pigment deposition in the posterior corneal stroma and endothelium. In addition, there is pigmentation in a stellate pattern on the anterior lens and lens capsule. This rarely causes a decrease in visual acuity.

These findings are characteristic of long-term thorazine use and are suspected to be related to dose and duration of treatment. It is recommended that persons undergoing long-term treatment with thorazine have regular eye examinations.

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current03:10, April 13, 2022Thumbnail for version as of 03:10, April 13, 2022800 × 534 (51 KB)Drklai (talk | contribs)Contributor: Elizabeth Gauger, MD Photographer: D. Brice Critser, CRA, OCT-C Corneal and lenticular pigmentation from long-term chlorpromazine use 59-year-old male with history of schizophrenia and long-term chlorpromazine (thorazine) treatment. His ocular exam is notable for fine pigment deposition in the posterior corneal stroma and endothelium. In addition, there is pigmentation in a stellate pattern on the anterior lens and lens capsule. This rarely causes a decrease in visual acuity. T...

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