File:CTLA-4.png

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Within the lymph node (priming phase): Dendritic cell-T cell interaction with self-antigen presented (immune checkpoint) – the major histocompatibility complex- T cell receptor complex and the B7/CD28 complex provide activation signals to activate the T cell, but the Cytotoxic T lymphocyte Antigen 4 (CTLA-4)/B7 complex inhibits the activation so the T cell is not activated.

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current06:51, June 5, 2021Thumbnail for version as of 06:51, June 5, 20212,291 × 2,594 (429 KB)Subahari.Raviskanthan (talk | contribs)

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