Featured Article for December 31, 2015
Age-releated macular degeneration is an acquired degeneration of the retina that causes significant central visual impairment through a combination of nonneovascular (drusen and retinal pigment epithelium abnormalities), and neovascular derangement (choroidal neovascular membrane formation). Advanced disease may involve focal areas of retinal pigment epithelium (RPE) loss, subretinal or sub-RPE hemorrhage or serous fluid, as well as subretinal fibrosis.