EyeWiki:Featured article/December 15, 2019

From EyeWiki

Featured Article for December 14, 2019

Morning Glory anomaly

The morning glory disc anomaly can be seen with transsphenoidal basal encephalocele. In the basal encephalocele, a congenitally malformed outpouching of the meninges, often containing the optic chiasm and hypothalamus, protrudes through a defect in the sphenoid bone. Children with this structural defect often have dysmorphic features, including a wide head, flat nose, hypertelorism and a midline notch in the upper lip. Many patients with transsphenoidal encephalocele also have callosal agenesis, leading to dilation of the lateral ventricles.

Morning glory disc anomaly is also associated with cerebrovascular anomalies, including hypoplasia of the cerebral arteries and Moyamoya. Other reported associations include with the PHACE syndrome (posterior fossa malformation, large facial hemangioma, arterial anomalies, cardiac anomalies, eye anomalies) and neurofibromatosis 2.

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