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The Eye Encyclopedia written by Eye Physicians & Surgeons

EyeWiki is an ophthalmic wiki where ophthalmologists, other physicians, patients and the public can view an eye encyclopedia written by ophthalmologists covering the vast spectrum of eye disease, diagnosis and treatment. Any qualified ophthalmologist or ophthalmologist in training is invited to contribute content to the wiki and post it immediately. For content guidelines and more information see About EyeWiki and Getting Started. EyeWiki is a collaboration between the American Academy of Ophthalmology and these societies.

Featured Article for October 31, 2022

Cytomegalovirus Anterior Uveitis

CMV anterior uveitis is caused by cytomegalovirus, which is a DNA virus that is a member of the Herpesviridae family. Primary CMV infection is common and often subclinical in immunocompetent individuals. Typically, it causes a mild flu-like illness. Like other Herpesviridae (e.g. Herpes Simplex Virus (HSV), Varicella-Zoster Virus (VZV), and Epstein-Barr Virus) CMV evades immune surveillance and establishes latency. Because CMV lies latent in myeloid progenitor cells, it is thought that CMV anterior uveitis is due to viral reactivation in anterior chamber monocytes in patients who are ill and mounting a systemic immune response.

<Featured article/May 15, 2022

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Article of the Day

Today's article of the day is Voretigene neparvovec-rzyl (Luxturna™), contributed by Asdrubal Moreno

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EyeWiki Editor-in-Chief, Brad Feldman, MD, discusses the thinking behind the EyeWiki initiative with the American Medical Association Journal of Ethics.
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